Motif ID: NFY{A,B,C}.p2

Z-value: 4.357


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYCchr1_+_409302330.765.6e-04Click!
NFYAchr6_+_411488690.292.7e-01Click!
NFYBchr12_-_103055924-0.068.2e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_139084833 6.378 NM_178448
C9orf140
chromosome 9 open reading frame 140
chr9_+_130883199 5.531 NM_001135917
NM_020438
DOLPP1

dolichyl pyrophosphate phosphatase 1

chr12_-_120725210 5.401 LOC338799
hypothetical LOC338799
chr19_+_19035792 5.307 NM_178526
SLC25A42
solute carrier family 25, member 42
chr17_+_43374021 4.981 PNPO
pyridoxamine 5'-phosphate oxidase
chr20_-_45418818 4.760 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr17_+_54587882 4.705 PRR11
proline rich 11
chr17_+_43373887 4.684 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr20_-_538909 4.547 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr17_+_54587641 4.489 NM_018304
PRR11
proline rich 11
chr19_+_1442000 4.486 NM_138393
REEP6
receptor accessory protein 6
chr7_+_99974781 4.383 AGFG2
ArfGAP with FG repeats 2
chr7_+_99974720 4.278 NM_006076
AGFG2
ArfGAP with FG repeats 2
chrX_+_47999740 4.146 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr16_-_2204776 4.053 NM_001042371
PGP
phosphoglycolate phosphatase
chr22_+_36384647 3.999 NM_020315
PDXP
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr11_-_73371945 3.891 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr17_+_23670247 3.887 NM_014573
TMEM97
transmembrane protein 97
chr7_-_156495985 3.849 NM_005515
MNX1
motor neuron and pancreas homeobox 1
chr17_-_54587581 3.748 NM_001100595
NM_182620
SKA2

spindle and kinetochore associated complex subunit 2


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 114 entries
enrichment   p-value GO term description
6.92 2.62e-02 GO:0000085 G2 phase of mitotic cell cycle
6.92 2.62e-02 GO:0051319 G2 phase
5.82 2.90e-03 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
4.94 2.98e-04 GO:0006271 DNA strand elongation involved in DNA replication
4.61 8.90e-04 GO:0022616 DNA strand elongation
4.49 5.18e-04 GO:0006695 cholesterol biosynthetic process
4.36 5.37e-14 GO:0006334 nucleosome assembly
4.25 2.04e-15 GO:0065004 protein-DNA complex assembly
4.24 7.77e-14 GO:0031497 chromatin assembly
4.13 1.06e-13 GO:0034728 nucleosome organization
4.11 4.37e-15 GO:0071824 protein-DNA complex subunit organization
4.06 1.15e-03 GO:0016126 sterol biosynthetic process
3.96 3.45e-04 GO:0000819 sister chromatid segregation
3.94 1.44e-15 GO:0006323 DNA packaging
3.81 1.52e-08 GO:0000236 mitotic prometaphase
3.77 3.77e-03 GO:0000070 mitotic sister chromatid segregation
3.75 8.11e-15 GO:0006333 chromatin assembly or disassembly
3.65 3.84e-15 GO:0071103 DNA conformation change
3.61 1.15e-09 GO:0007059 chromosome segregation
3.30 2.17e-16 GO:0000075 cell cycle checkpoint

Gene overrepresentation in compartment category:

Showing 1 to 20 of 58 entries
enrichment   p-value GO term description
9.89 4.84e-02 GO:0000800 lateral element
7.06 3.39e-05 GO:0042613 MHC class II protein complex
6.29 1.12e-02 GO:0000780 condensed nuclear chromosome, centromeric region
4.78 8.35e-12 GO:0000786 nucleosome
4.71 6.14e-03 GO:0000795 synaptonemal complex
3.98 2.41e-12 GO:0032993 protein-DNA complex
3.78 1.40e-05 GO:0000794 condensed nuclear chromosome
3.42 1.91e-06 GO:0000779 condensed chromosome, centromeric region
3.39 3.19e-05 GO:0000922 spindle pole
3.31 5.07e-20 GO:0000785 chromatin
3.25 3.40e-11 GO:0000775 chromosome, centromeric region
3.25 6.34e-11 GO:0000793 condensed chromosome
3.25 4.28e-05 GO:0000777 condensed chromosome kinetochore
3.22 2.53e-06 GO:0000776 kinetochore
3.15 3.09e-02 GO:0000792 heterochromatin
3.08 6.89e-33 GO:0044427 chromosomal part
3.08 1.03e-11 GO:0044454 nuclear chromosome part
3.02 1.80e-37 GO:0005694 chromosome
2.83 1.65e-11 GO:0000228 nuclear chromosome
2.83 4.11e-02 GO:0016605 PML body

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
2.78 2.89e-02 GO:0008094 DNA-dependent ATPase activity
2.27 1.23e-04 GO:0003682 chromatin binding
1.57 5.24e-06 GO:0030528 transcription regulator activity
1.56 2.51e-16 GO:0003677 DNA binding
1.48 2.72e-19 GO:0003676 nucleic acid binding
1.47 9.48e-04 GO:0001071 nucleic acid binding transcription factor activity
1.47 9.48e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.46 2.26e-02 GO:0019899 enzyme binding
1.43 3.32e-02 GO:0003723 RNA binding
1.16 8.72e-07 GO:0005515 protein binding
1.14 2.95e-02 GO:0003824 catalytic activity
1.12 7.66e-14 GO:0005488 binding